The ICD-10-CM (International Classification of Diseases, Tenth Revision, Clinical Modification) coding system, the standard for classifying diagnoses and inpatient procedures which is crucial for clinical documentation and billing, brings a fresh set of changes for FY 2025. There are over 300 code changes — 252 new codes, 13 deletions, and 36 revisions. These revisions, effective October 1, 2024, reflect the latest advancements happening in the healthcare industry.
Chapter-wise Classification
Breaking down the chapter-wise code updates
| Chapter | New Codes Added | Deletions | Revisions |
|---|---|---|---|
| Chapter 1: Certain Parasitic and Infectious Diseases | 0 | 0 | 1 |
| Chapter 2: Neoplasms | 63 | 14 | 0 |
| Chapter 3: Diseases of the Blood and Blood-Forming Organs | 1 | 0 | 0 |
| Chapter 4: Endocrine, Nutritional, and Metabolic Diseases | 16 | 2 | 0 |
| Chapter 5: Mental, Behavioral and Neurodevelopmental Disorders | 26 | 4 | 1 |
| Chapter 6: Diseases of the Nervous System | 7 | 1 | 1 |
| Chapter 7: Diseases of the Eye and Adnexa | 0 | 0 | 5 |
| Chapter 8: Diseases of the Ear and Mastoid Process | 0 | 0 | 0 |
| Chapter 9: Diseases of the Circulatory System | 4 | 0 | 2 |
| Chapter 10: Diseases of the Respiratory System | 7 | 0 | 0 |
| Chapter 11: Diseases of the Digestive System | 27 | 3 | 1 |
| Chapter 12: Diseases of the Skin and Subcutaneous Tissue | 8 | 3 | 0 |
| Chapter 13: Diseases of the Musculoskeletal System and Connective Tissue | 33 | 3 | 0 |
| Chapter 14: Diseases of the Genitourinary System | 0 | 0 | 0 |
| Chapter 15: Pregnancy, Childbirth, and the Puerperium | 0 | 0 | 0 |
| Chapter 16: Certain Conditions Originating in the Perinatal Period | 0 | 0 | 0 |
| Chapter 17: Congenital Malformations, Deformations and Chromosomal Abnormalities | 4 | 1 | 1 |
| Chapter 18: Symptoms, Signs, and Abnormal Clinical and Laboratory Findings, Not Elsewhere Classified | 1 | 0 | 0 |
| Chapter 19: Injury, Poisoning, and Certain Other Consequences of External Causes | 30 | 3 | 0 |
| Chapter 20: External Causes of Morbidity | 0 | 0 | 0 |
| Chapter 21: Factors Influencing Health Status and Contact with Health Services | 25 | 2 | 1 |
| Chapter 22: Codes for Special Purposes | 0 | 0 | 0 |
| Total | 252 | 36 | 13 |
Some of the most significant changes were implemented to coding of neoplasms (C00-D49), that included the addition of 63 new codes to specify when lymphoma is in remission. These new codes provide clarity for distinct types of lymphoma in remission, enabling a fair comparison to assess patient care, statistical data and resource consumption.
Key Takeaways of the Code Updates
Below are some of the key takeaways from the 2025 ICD-10-CM updates:
- Diabetes Updates: Three new diagnosis codes (E10.A10 – E10.A12) were added to capture early-stage diagnosis of presymptomatic Type 1 Diabetes. This highlights the significance of identifying diabetes before symptoms appear. Three new codes were also added for hypoglycemia levels (E16.A1 — E16.A3).
- Lymphoma in Remission: As mentioned earlier, 63 codes were added for the precise identification of lymphoma, in both active and remission stages. These codes were expanded with a fifth character to indicate if the lymphoma is “in remission.”
- Fanconi Anemia: This rare genetic order which affects the bone marrow, has now found its own place among the ICD-10-CM ‘25 updates (D61.03). This allows for better tracking of this condition and is classified as a CC for FY 2025.
- Personal History of Polyps: Addition of 4 new codes has now expanded the ICD-10-CM code set for personal history of polyps. The personal history of polyps can be classified as non-neoplastic (typically non-cancerous) and neoplastic (have the possibility to develop cancer). The new codes (Z86.0100 — Z86.0102 and Z86.0109) will help provide specificity for individuals with risk factors.
- Congenital Heart Conditions: Introduction of codes for bicuspid aortic valve (Q23.81) and other congenital heart malformations (Q23.82 and Q23.88) will aid healthcare providers to track these conditions and prevent complications. For the new code Q23.81, a tabular note to code is present for acquired aortic valve disorders, such as: aortic insufficiency (I35.1), aortic stenosis (I35.0), and aortic stenosis with insufficiency (I35.2); if applicable.
- Obesity Classifications: For specifying various classes of obesity, 4 new ICD-10-CM diagnosis codes (E66.811—E66.89) have been added, which will allow for better monitoring and tracking of obesity’s impact on health.
- Eating Disorders: Enhanced specificity in eating disorder ICD-10-CM diagnosis codes (F50.010—F50.029) now differentiates between restricting and binge-purge types of anorexia, providing greater clarity for clinicians. Also, codes will specify if mild, moderate, severe, or extreme anorexia.
- Pulmonary Embolism Expansion: Addition of four new codes for fat and cement pulmonary embolism (I26.03-I26.04 and I26.95-I26.96) is bound to provide improved diagnosis and treatment.
- KCNQ2-Related Epilepsy: Four new codes (G40.43X-) have been added for healthcare providers to treat one of the most common genetic epilepsy syndromes that affect children, with more precision.
- Nasal Valve Collapse: Seven new codes have been added to differentiate between internal or external nasal valve collapse and if the collapse is static or dynamic (J34.82).
The 2025 ICD-10-CM code updates project the ever-evolving needs of patients and healthcare providers alike while covering every aspect of general & mental health, chronic conditions, with enhanced accuracy. As a medical coding services company, it is our responsibility to keep up with the regular updates and understand how to use them appropriately. This helps ensure compliance and enhances patient care for your healthcare practice.
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